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לוי וארדי רונן- מנהל פנימית ג

 

Professional education

 

1987- 1990     Hebrew University, Jerusalem. Life Sciences. BSc

1991- 1997     Semmelweis University of Medicine, Budapest. Medicine. MD

 

 

Professional trainings

 

1998- 1999     Hadassah Medical Center. Rotating internship

1999- 2003     Hadassah Medical Center. Residency in Internal Medicine

2005- 2007     Hadassah Medical Center. Residency in Nephrology and Hypertension

 

Hospital appointment

 

2007- 2016     Attending, Nephrology and hypertension services, Hadassah Medical Center

2017- present Attending, Nephrology and hypertension, Barzilai Medical Center

 

 

 Academic appointments

 

2005- 2010     Clinical instructor in Internal Medicine

2011- 2016     Lecturer in Internal Medicine at the Hebrew University School of Medicine in Jerusalem

2017-present   Lecturer in Internal Medicine at the Ben Gurion University of the Negev

 

 

Certifications

 

2004 Israeli boards of internal medicine and nephrology

2007 Israeli boards of Nephrology and hypertension

2018 Good Clinical Practice

 

Teaching responsibilities

 

1999-2003    Physical diagnosis for medical students [4th (course No 96713) and 6th  years]

1999-2016    Internal Medicine for medical students (4th and 6th years) at the Hebrew University School of Medicine in Jerusalem

2005-2016    Introductory course in internal medicine to 4th year medical students- nephrology. Course No 96713 at the Hebrew University School of Medicine in Jerusalem

2005-2016    Nephrology for 6th year medical students at the Hebrew University Scholl of Medicine in Jerusalem

2009- 2016   Molecular mechanisms in kidney physiology in health and disease, course No 94412, for MSc and PhD students at the Hebrew University School of Medicine in Jerusalem

2010- 2016   Pathology of Diseases, course No 64861, for 3rd year pharmacy students at the Hebrew University School of Medicine

 2017- 2018  Nephrology course for students of the International School of Medicine of the Health Science faculty at the Ben-Gurion University in the Negev

2017- 2020   Nephrology for 2nd year pharmacy students at the Pharmacy School of the Health Science faculty at the Ben-Gurion University in the Negev

2018- 2020   Advanced nursing care at Barzilai University Medical Center

2017- present Nephrology for 3rd year medical students at the Ben-Gurion School of Medicine of the Health Science faculty at the Ben-Gurion University in the Negev

2017- present Nephrology rounds for 5th year medical students at the Health Science Faculty School of Medicine of the Ben-Gurion University in the Negev

 

 

Awards

 

2016 מענק קרן גישור בנושא:  Mechanism of regulation of fibroblast growth factor 23 in experimental models of acute and chronic kidney disease

         

2013 Letter of appreciation for excellence in teaching from the dean of the        Hebrew University of Medicine

 

2011 Israeli Society of Nephrology scholarship for research on the regulation of FGF23 in states of chronic kidney failure

 

2008 Title of excellent medical instructor of the Faculty of Medicine of the Hebrew University of Medicine

 

2007 Faculty Award of the Faculty of Medicine of the Hebrew University and Hadassah Medical Center for excellence in clinical work.

 

2003 Title of excellent medical instructor of the Faculty of Medicine of the Hebrew University of Medicine 

 

2003- 2005 Physician Research Scholarship

 

 

Committee membership in the Hebrew University

 

2008- 2012     Member of the committee writing the final exam in Internal Medicine for the 6th year students in the Hebrew University

 

 

List of Publications

Refereed articles in scientific journals

1.      Chana Yagil, Ronen Varadi-Levi, Chen Ifrach and Yoram Yagil., Dysregulated UPR and ER Stress Related to a Mutation in the Sdf2l1 Gene Are Involved in the Pathophysiology of Diet-Induced Diabetes in the Cohen Diabetic Rat. International Journal of Molecular Sciences 2023 24, 1355

2.      Larissa Lebedev, Marina Sapojnikov, Alexander Vechsler, Ronen Levi-Vardi, Doron Zamir, Ana Tovar, Nomy Levin-Yaina, Shlomo Fytlovich, Yoram Yagil., Minimal Change Disease Following the Pfizer-BioNTech COVID-19 Vaccine. American Journal of Kidney Diseases 2021 78(1): 142-145

 

  1. Chana Yagil, Ronen Varadi-Levi, Yoram Yagil., A novel mutation in the NADH dehydrogenase (ubiquinone) 1 alpha subcomplex 4 (Ndufa4) gene links mitochondrial dysfunction to the development of diabetes in a rodent model. Disease Models & Mechanisms 2018 11: 1-9

4.      Durlacher-Betzer K, Hassan A, Levi R, Axelrod J, Silver J, Naveh-Many T., Interleukin-6 contributes to the increase in fibroblast growth factor 23 expression in acute and chronic kidney disease.  Kidney Int. 2018 Aug;94(2):315-325

 

  1. Alia Hassan, Karina Durlacher, Justin Silver, Tally Naveh-Many and Ronen Levi., The fibroblast growth factor receptor mediates the increased FGF23 expression in acute and chronic uremia. Am J Physiol Renal Physiol 2016 Feb 1;310(3): F217-21

 

  1. Khoury T, Yosha L, Abu Ramieleh A, Schneider R, Wolf DG, Levi R., A heart breaking case of rapidly developing severe hemophagocytic syndrome secondary to chronic active EBV infection; a case report and review of the literature. Journal of Clinical Virology. 2015 67: 14-16

 

  1. Meir T, Levi R, Lieben L, Libutti S, Carmeliet G, Bouillon R, Silver J, Naveh-Many T., Deletion of the vitamin D receptor specifically in the parathyroid demonstrates a limited role for the VDR in parathyroid physiology. Am J Physiol Renal Physiol. 2009 Aug; (Epub ahead of print). 3.9

 

  1. Ronen Levi, Iddo Z. Ben-Dov, Vardit Lavi-Moshayoff, Maya Dinur, David Martin, Tally Naveh-Many, Justin Silver., Increased PTH gene expression in secondary hyperparathyroidism of experimental uremia is reversed by calcimimetics: Correlation with post-translational modification of the trans acting factor AUF1. Journal of the American Society of Nephrology 2006 17(1): 107-112. 7.63

 

  1. Osnat Bell, Elena Gaberman, Rachel Kilav, Ronen Levi, Keith B. Cox, Jeffery D. Molkentin, Justin Silver, and Tally Naveh-Many., The Protein Phosphatase Calcineurin Determines Basal Parathyroid Hormone Gene Expression. Mol Endocrinol 2005 19: 516-526. 5.2

 

  1. Moz Yulia, Levi Ronen, Lavi Moshayoff V, Cox KB, Molkentin JD, Siver J, Naveh-Many T., Calcineurin A beta is central to the expression of the renal type II Na/Pi co-transporter gene and to the regulation of renal phosphate transport. J Am Soc Nephrol. 2004 Dec;15(12):2972-80. 7.6

 

  1. Moz Yulia, Levi Ronen, Lavi Moshayoff V, Cox KB, Molkentin JD, Siver J, Naveh-Many T., Protein-RNA interactions determine the stability of the renal NaPi-2 cotransporter mRNA and its translation in hypophosphatemic rats. J Biol Chem. 1999 Sep 3: 274(36):25266-72. 5.3

 

 

Reviews

 

  1. רונן לוי-ורדי, יורם יגיל. יתר לחץ דם כגורם למחלת כליה- האמנם? הרפואה כרך 159 חוברת 12 דצמבר 2020, עמודים 887- 891

 

  1. Ronen Levi, Yoram Yagil., Vitamin D, hypertension and ischemic stroke: an unresolved relationship. Hypertension, 2017 Sep: 1-3

 

3.      Khoury T, Tzukert K, Abel R, Abu Rmeileh A, Levi R, Ilan Y., The gut-kidney axis in chronic renal failure: A new potential target for therapy. Hemodial Int. 2016 Sep 16 (Epub ahead of print)

 

  1. Levi R, Silver J., Vitamin D supplementation after kidney transplantation. How much vitamin D should we prescribe? Kidney Int. 2009 Mar; 75(6):576-578. Review. 6

 

  1. Ronen Levi, Anca Gal-Moscovici., Renal osteodystrophy in peritoneal dialysis: special considerations. Peritoneal dialysis international. 2008, 28: S11-S19

 

  1. Silver J, Levi R., Regulation of PTH synthesis and secretion relevant to the management of secondary hyperparathyroidism in chronic kidney disease. Kidney Int. Suppl. 2005 Jun;(95): S8-12. Review. 6

 

  1. Ronen L, Silver J., Pathogenesis of parathyroid dysfunction in end-stage kidney disease. Pediatr Nephrol. 2005 Mar;20(3):342-5. Epub 2004 Nov 10. Review. 2.4

 

 

Chapters in Books

 

  1. Yoram Yagil, Ronen Levi Varadi, Chana Yagil, Genomic research in rat models of kidney disease, Methods in molecular biology (not published yet)

 

  1. Ronen L, Silver J., Hypercalcemia in Oxford Textbook of Endocrinology and Diabetes 2nd edition, September 25, 2011. Bilezikian J, editor. Oxford University Press, Oxford, p 642

 

  1. Ronen L, Hyperparathyroidism in Elsevier's First Consult- evidence based answers for the point of care, Sept 2010

 

                                                                                                       

Presentations at national and international conferences

 

 

1.      Poster at the American Society of Nephrology Annual Meeting Nov 2016: "IL-6 acts on bone to increase FGF-23 expression in acute and chronic renal failure and in vitro"

 

  1. American Society of Nephrology Annual Meeting Nov 2015. Lecture on: "The fibroblast growth factor receptor mediates the increased FGF23 expression in acute and chronic uremia"

 

  1. Israeli Society of Nephrology Annual Meeting March 2015. Lecture on: "FGF23 in Acute Kidney Injury"

 

  1. Israeli Society of Nephrology Board Review Oct. 2010. Lecture on:  "Potassium Disorders- clinical emergencies"

 

  1. Israeli Society of Nephrology Annual Meeting May 2010. Lecture on: "De Novo Glomerulonephritis in Kidney Transplant Patients- Case Presentation and Review of the Literature"

 

  1. American Society of Nephrology Annual Meeting 2004. Lecture on: "The Protein Phosphatase Calcineurin Aβ Determines PTH Gene Expression" Oral presentation

 

  1. Israeli Society of Nephrology Annual Meeting 2003. Lecture on: "Secondary hyperparathyroidism and regulation of PTH gene expression in a rat model of renal failure"
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